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Adrenocortical Carcinoma with Pancreatic Metastasis in a Pediatric Patient: A Case Report (top 2)

Bob Balmores, MD
Esther Saguil, MD*


Adrenocortical carcinoma (ACC) is a rare malignancy. The patient, a 15-year old female, is a case of ACC with pancreatic metastasis who presented with vague abdominal pain. She was initially managed as pheochromocytoma based on imaging and elevated metanephrine level. Patient was advised surgery but due to absence of symptoms of pheochromocytoma, patient opted to undergo observation. Series of whole abdominal CT scans were done which showed bilateral adrenal gland masses and a pancreatic head mass. Biopsy of the pancreatic mass was done which showed benign results. Due to persistence of adrenal and pancreatic mass, patient underwent Whipple‘s procedure with right adrenalectomy. Histopathology showed adrenocortical cancer of the right adrenal gland with metastasis to pancreas. This represents the first known reported case of a pancreatic metastasis of a pediatric adrenocortical carcinoma.
Keywords: Adrenocortical carcinoma, Non-functioning adrenocortical carcinoma, Pancreatic metastasis,Pheochromocytoma

*Adviser/Consultant, Department of Surgery